Hiv Medicines

Nevivir 200 mg tablets contain nevirapine, which is an antiretroviral medication used in the treatment of HIV (human immunodeficiency virus). Nevirapine belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs). Here's an overview of what you need to know about Nevivir:

1. Mechanism of Action:

   • Nevirapine works by inhibiting the reverse transcriptase enzyme, which is crucial for the replication of HIV. By blocking this enzyme, nevirapine prevents the virus from converting its RNA into DNA, thereby halting its ability to reproduce.

2. Uses:

   • HIV Treatment: Nevirapine is used in combination with other antiretroviral medications to manage HIV infection. It helps to reduce the viral load in the blood, increase CD4 cell counts, and improve immune function.

3. Dosage:

   • Adults: The typical starting dose is 200 mg once daily for the first 14 days to assess tolerance. After the initial period, the dose is usually increased to 200 mg twice daily.
   • Children: Dosage is based on body weight and must be determined by a healthcare provider.
   • Adjustment: Dosages may be adjusted based on individual tolerance, side effects, and drug interactions.

4. Administration:

   • Tablets should be taken orally with or without food. Consistency in taking the medication at the same time each day is important for effectiveness.

5. Side Effects:

   • Common: Rash, nausea, headache, and fatigue.
   • Serious: Nevirapine can cause severe liver problems (hepatitis), skin reactions (including Stevens-Johnson syndrome), and potentially life-threatening rashes. Regular monitoring of liver function is important.
   • Other: May also lead to changes in lipid levels or blood counts.

6. Precautions:

   • Liver Function: Regular liver function tests are required due to the risk of hepatotoxicity. Patients with pre-existing liver conditions or a history of hepatitis should use nevirapine with caution.
   • Allergic Reactions: Be aware of signs of serious allergic reactions or rash. Discontinue use and seek medical advice if severe reactions occur.
   • Drug Interactions: Nevirapine can interact with other medications, including some antibiotics, antifungals, and other HIV medications. Inform your healthcare provider about all medications you are taking.

7. Pregnancy and Breastfeeding:

   • Pregnancy: Nevirapine is categorized as a Category B drug, meaning there is no evidence of risk in humans, but it should still be used during pregnancy only if clearly needed and prescribed by a healthcare provider.
   • Breastfeeding: It is generally recommended that HIV-positive mothers do not breastfeed to avoid transmitting the virus to the baby. However, if a breastfeeding mother is on nevirapine, she should consult her healthcare provider for guidance.

8. Monitoring:

   • Regular follow-up appointments are necessary to monitor viral load, CD4 count, and any potential side effects. Adjustments to the medication regimen may be required based on these assessments.